Complete OSCE Skills for Medical and Surgical Finals 2nd Edition PDF ebook


SKU: 9781138099821 Category:

Buy Complete OSCE Skills for Medical and Surgical Finals 2nd Edition PDF ebook by author Kate Tatham published by CRC Press in 2018 and save up to 80%  compared to the print version of this textbook. With PDF version of this textbook, not only save you money, you can also highlight, add text, underline add post-it notes, bookmarks to pages, instantly search for the major terms or chapter titles, etc.
You can search our site for other versions of the Complete OSCE Skills for Medical and Surgical Finals 2nd Edition PDF ebook. You can also search for others PDF ebooks from publisher CRC Press, as well as from your favorite authors. We have thousands of online textbooks and course materials (mostly in PDF) that you can download immediately after purchase.
Note: e-textBooks do not come with access codes, CDs/DVDs, workbooks, and other supplemental items.
eBook Details:

Full title: Complete OSCE Skills for Medical and Surgical Finals 2nd Edition
Edition: 2nd
Copyright year: 2018
Publisher: CRC Press
Author: Kate Tatham
ISBN: 9781138099821, 9789813222977
Format: PDF

Description of Complete OSCE Skills for Medical and Surgical Finals 2nd Edition:
This exciting new book explores the dark side of the molecular protein assembly bringing an updated view of how failures in the homeostatic mechanisms that efficiently regulate protein folding leads to the accumulation of structurally abnormal pathogenic assemblies, encompassing an emerging group of diseases collectively known as ‘Protein Folding Disorders.’ This complex and diverse group of chronic and progressive entities are bridged together by their relationship to structural transitions in the native state of specific proteinaceous components, which for reasons poorly understood, convert into polymeric aggregates that generate poorly soluble tissue deposits and which are considered today the culprit of the disease pathogenesis in their respective diseases. Despite the diversity in the amino acid sequence of the different proteins involved in these heterogeneous disorders, all the pathologic conformers can trigger cascades of events ultimately resulting in cell dysfunction and death with devastating clinical consequences in many of the most precious aspects of human existence including personality, cognition, memory, and skilled movements.This book, which is composed of a compilation of chapters authored by outstanding and well-published scientists in the respective fields currently performing active investigations at world renowned universities and research centers, focuses on the growing number of diseases associated with protein misfolding in the central nervous system. Individual chapters are dedicated to the most common neurodegenerative diseases associated with protein aggregation/fibrillization focusing on the nature of the pathogenic species and the cellular pathways involved in the molecular pathogenesis of Alzheimer’s, Parkinson’s, and Huntington’s diseases as well as in Amyotrophic Lateral Sclerosis, and Prion disorders. A group of contributions is centered on the current knowledge of the intracellular pathways and subcellular organelles affected by the different disease conditions, while others are focused in the emerging pathogenic role of misfolded subunits assembled into neurotoxic soluble oligomers, and in the novel notion of the transmissibility of the protein misfolded species, an innovative concept until recently only accepted for Prion diseases. Lastly, a different set of chapters is dedicated to the evaluation of novel therapeutic strategies for these devastating diseases.


There are no reviews yet.

Be the first to review “Complete OSCE Skills for Medical and Surgical Finals 2nd Edition PDF ebook”

Your email address will not be published. Required fields are marked *